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Changsha Herbal Ingredient Co., Ltd.

Apigenin, Chamomile Extract, Antioxidant manufacturer / supplier in China, offering Natural Apis Apigenin for Anti-Inflammatory, Blueberry Extract with 25%Anthocyanin for Health Food, 100%Natural Gastrodia Elata Extract Gastrodin for Foods Supplement and so on.

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Supplier Homepage Product APIs Natural Apis Apigenin for Anti-Inflammatory

Natural Apis Apigenin for Anti-Inflammatory

Purchase Qty.:
(kg)
1-4 5-24 25-99 100+
FOB Unit Price: US $40 US $39 US $38 US $36
Purchase Qty. (kg) FOB Unit Price
1-4 US $40
5-24 US $39
25-99 US $38
100+ US $36
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Port: Changsha, China
Production Capacity: 20ton/Year
Payment Terms: L/C, T/T, Western Union

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Basic Info
  • Model NO.: CHI-APIs
  • Assay Method: HPLC
  • Application: Food, Health Care Products, Medicine, Cosmetics
  • Extract Source: Chamomile
  • Lead Time: Within 5 Working Days
  • Used for: Anti-Inflammatory and Anticancer Properties
  • Transport Package: 5kg/Bag, 25kg/Drum
  • Origin: P. R. China
  • Certification: ISO, FDA, cGMP
  • Application Form: Tablet, Capsule
  • State: Powder
  • MOQ: 1kg
  • Shipping Way: by Air, by DHL
  • Trademark: CHI
  • Specification: 1%-98%Apigenin
  • HS Code: 130219
Product Description
1. Sources and Habitation
Natural Apis Apigenin for Anti-Inflammatory
Apigenin (4,5,7-trihydroxyflavone),  is a natural product belonging to the flavoneclass  that  is the aglycone  of  several naturally occurring glycosides.It is found in high amounts in several herbs including parsley, thyme, and peppermint. 
 
It is is also found in a number of other herbs, including chamomile herb, Horsetail herb, lemon balm herb, perilla herb, vervain herb, and yarrow.
 
Red wine and tomato sauce contain this flavonoid.
 
2. Descriptions and Specifications of Product
Plant original: Apium graveolens var.dulce 
Specifications: 98.0% Apigenin Test by HPLC
Molecular Formula: C15H10O5
Molecular Mass: 270.24
CAS No: 520-36-5
Natural Apis Apigenin for Anti-Inflammatory

 
 
3. Indications and Uses
Apigenin is an antioxidant plant flavanoid which contains anti-inflammatory  and anticancer properties.  It may induce apoptosis and may inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase. 

Apigenin 
Is also known to be a MAP kinase inhibitor and a selective inhibitor of Protein Kinase 2 (CK2). Apigenin is capable of exerting diverse effects on a vast variety of molecular targets. Most effects appear to be mostly mediated through suppressing nitric oxide synthase-2 (NOS2), Hypoxia-inducible factor 1 α (HIF-1α), lipoxygenase, cyclooxygenase-2 (COX-2)  and  vascular  endothelial growth factor (VEGF) expression. Blocks proliferation of Wnt-1 transfected cells,  dephosphorylates β-catenin and lowers levels of β-catenin  and Dvi. Apigenin is  an inhibitor  of Casein Kinase, CYP19, CYP2C9, ERK and PKC.
 
4. Safety Concerns
Apigenin seems to be very safe chemical, without any dangerous side effects, flavonoid can interact with chemotherapy drugs. 
 
It is, by itself, a potent chemotherapeutic agent.
 
5. Dosage Information
For general health and well-being, doses found in multiple servings of fruits and vegetables is adequate.For anxiolytic effects, doses in the range of 3-10 mg/kg  bodyweight  are effective without  sedation,  and higher doses induce sedation in addition to reductions in anxiety.
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